The Kansas City Region


The Kansas City Region sits on the Missouri River, at the crossroads of four major interstates, three major highways and five Class 1 rail lines, and is served by the Kansas City International Airport, which opened its new, state-of-the-art terminal in 2023. This combination of logistical assets offers direct connections to markets across North America and around the world.

The region is one of the two key automotive manufacturing hubs in Missouri, producing both the Ford F-150 and the Ford Transit vans. More than 230,000 Ford F-150s were built in the region in 2022.

The Kansas City Region is also in the center of the Animal Health Corridor, a key area of strength for Missouri in the agtech and health innovation sectors. Regional companies represent 56 percent of the worldwide sales of animal health products.

Cerner, Hallmark and H&R Block call this area home, with more companies joining them all the time, especially in the areas of health innovation, logistics and financial services.

The region is known for its vibrant quality of life with the World Series Champion Kansas City Royals, the Superbowl Champion Kansas City Chiefs, downtown and midtown entertainment and shopping districts, and an affinity for fine jazz and delicious food.

Major Cities
  • Kansas City (Pop: 509,297)
  • Independence (121,202)
  • Lee’s Summit (103,465)
  • Blue Springs (59,518)
  • Liberty (30,775)
  • Raytown (29,312)
  • Gladstone (26,907)
  • Grandview (25,610)

Source: U.S. Census Bureau, 2022


Key Employers
  • American Century Investments (Kansas City)
  • Blue Cross Blue Shield of Kansas City (Kansas City)
  • Burns & McDonnell (Kansas City)
  • Catalent Pharma Solutions (Kansas City)
  • Commerce Bank (Kansas City)
  • CVS Health (Kansas City)
  • Evergy (Kansas City)
  • FedEx (Kansas City)
  • Federal Reserve Bank of Kansas City (Kansas City)
  • Ford (Kansas City)
  • Freightquote (Kansas City)
  • H&R Block (Kansas City)
  • Hallmark (Kansas City)
  • Honeywell (Kansas City)
  • JE Dunn Construction (Kansas City)
  • Kansas City Southern (Kansas City)
  • LMV Automotive (Liberty)
  • Lockton (Kansas City)
  • Mars Petcare US (Kansas City)
  • Olin Winchester Lake City Ammunition Plant (Independence)
  • Oracle Cerner (Kansas City)
  • SS&C Technologies (Kansas City)
  • State Street (Kansas City)
  • UMB Financial Corp (Kansas City)
  • Union Pacific Railroad (Kansas City)
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