The Cape Girardeau Region


The Cape Girardeau region in southeast Missouri has long been an area of vibrant commerce and abundance, and a major transportation hub.

The region is home to five port facilities, seven major highways, Class I rail and a regional airport catering to virtually every type of business. The region has significant strengths in advanced manufacturing, agtech, and financial and professional services.

And the region is continually investing in its more than 160,000 strong labor force and business development via training, high quality universities and the regional Innovation Academy.

Major Cities
  • Cape Girardeau (Pop: 39,820)
  • Farmington (18,295)
  • Sikeston (16,135)
  • Jackson (15,515)
  • Kennett (10,288)
  • Perryville (8,475)

Source: U.S. Census Bureau, 2021


Key Employers
  • Arcosa Marine Products (Caruthersville)
  • Centene Corp. (Farmington)
  • Delta Companies, Inc. (HQ Cape Girardeau)
  • Gilster Mary-Lee (McBride and Perryville)
  • Havco Wood Products (Scott City)
  • Mississippi Lime Co (Ste. Genevieve)
  • Mondi Jackson Inc. (Jackson)
  • Orgill (Sikeston)
  • Piramal Glass (Park Hills)
  • Proctor & Gamble Paper Products (Jackson)
  • SRG Global (Farmington and Portageville)
  • Startek (Farmington)
  • TG Missouri Corp (Perryville)
  • Tyson Foods (Dexter)
  • Unilever (Sikeston)
  • US Tool Group (HQ Farmington)
  • WW Wood Products (Dudley)
Click to Learn More About Missouri’s Certified Work Ready Community
Download Missouri’s Workforce Data in Excel or PDF
Sites and Buildings
Click to find Missouri Buildings
Click to find Missouri Certified Sites


A Record Year 2022: Missouri Selected for Nation’s Premier Waste-to-Renewable Chemicals Facility

As 2022 draws to a close, we’re celebrating a record-breaking year at Missouri Partnership by ... Read More

Advanced Manufacturer Invests in Sikeston, Missouri

EnviCor Enterprises, an advanced manufacturer of rotationally molded plastic goods, announced p ... Read More

Advanced Manufacturer Invests in Kennett, Missouri

Cim-Tek Filtration, a leading manufacturer of filtration products, recently announced plans to ... Read More

View More