The Hannibal / Kirksville Region


The Hannibal/Kirksville Region sits on the Mississippi and is served by two interstate highways, four Class 1 railroads and regional airports, enabling efficient river, road, air and rail distribution in all directions. Four-lane US-36 also provides one of the fastest, least congested truck routes between Kansas City and Chicago.

The region is a prolific producer of soybeans, with additional strengths in advanced manufacturing, food solutions, information technology, and logistics.

Companies look to the region for competitive land and labor costs, favorable tax structures, and skilled vocational talent.

Major Cities
  • Hannibal: (Pop: 16,938)
  • Kirksville: (17,474)
  • Moberly: (13,774)
  • Warrenton: (9,176)

Source: U.S. Census Bureau, 2022

Key Employers
  • Ameriwood Industries (Wright City)
  • BASF (Palmyra)
  • Cerro Flow Products (Shelbina)
  • ConAgra Foods (Macon)
  • Continental Cement (Hannibal)
  • Daddy Ray’s (Moscow Mills)
  • Dura Automotive Systems (Moberly)
  • General Mills (Hannibal)
  • Independent Stave Company (New Florence)
  • The Kraft Heinz Company (Kirksville)
  • Onshore Outsourcing (Macon)
  • Orscheln Products (Moberly)
  • Saf-Holland USA (Warrenton)
  • Spartan Light Metal Products (Hannibal)
  • Toyota Motor Manufacturing, Missouri (Troy)
  • Watlow Electric (Hannibal)
  • Witte Bros. Exchange (Troy)
Click to Learn More About Missouri’s Certified Work Ready Community
Download Missouri’s Workforce Data in Excel or PDF
Sites and Buildings
Click to find Missouri Buildings
Click to find Missouri Certified Sites


Verde Resources Continues Growth After Missouri Northeast Expansion

Verde Resources, Inc, has announced a partnership with Green Carbon Industries (GCI), securing ... Read More

Missouri Certified Site: Moberly Area Industrial Park

Located in central Missouri, the Moberly Area Industrial Park is a 278-acre rail-served certifi ... Read More

Missouri Certified Site: Hannibal Lakeside Technology Park

Located in northeastern Missouri, Hannibal Lakeside Technology Park is home to a 116 acre certi ... Read More

View More

Economic Development Contacts