The Hannibal / Kirksville Region


The Hannibal/Kirksville Region sits on the Mississippi and is served by two interstate highways, four Class 1 railroads and regional airports, enabling efficient river, road, air and rail distribution in all directions. Four-lane US-36 also provides one the fastest, least congested truck routes between Kansas City and Chicago.

The region is a prolific producer of soybeans, with additional strengths in advanced manufacturing, food solutions, information technology, and logistics.

Companies look to the region for competitive land and labor costs, favorable tax structures, and skilled vocational talent.

Major Cities
  • Hannibal: (Pop: 17,246)
  • Kirksville: (17,653)
  • Moberly: (13,512)
  • Warrenton: (8,913)

Source: U.S. Census Bureau, 2020

Key Employers
  • Ameriwood Industries (Wright City)
  • BASF (Palmyra)
  • Cerro Flow Products (Shelbina)
  • ConAgra Foods (Macon)
  • Continental Cement (Hannibal)
  • Daddy Ray’s (Moscow Mills)
  • Dura Automotive Systems (Moberly)
  • General Mills (Hannibal)
  • Independent Stave Company (New Florence)
  • The Kraft Heinz Company (Kirksville)
  • Onshore Outsourcing (Macon)
  • Orscheln Products (Moberly)
  • Saf-Holland USA (Warrenton)
  • Spartan Light Metal Products (Hannibal)
  • Toyota Motor Manufacturing, Missouri (Troy)
  • Watlow Electric (Hannibal)
  • Witte Bros. Exchange (Troy)
Click to Learn More About Missouri’s Certified Work Ready Community
Download Missouri’s Workforce Data in Excel or PDF
Sites and Buildings
Click to find Missouri Buildings
Click to find Missouri Certified Sites


Advanced Manufacturer Invests in Hannibal, Missouri

Consolidated Machine and Welding recently announced plans to invest more than $4 million in its ... Read More

Missouri Northeast: Doers, Innovators & The Smartest Cities in Rural America

Are you a business looking to expand, or relocate, to a new location in the U.S.? If so, you kn ... Read More

Missouri Northeast: Grow, Make, Move, Connect

Are you a business owner looking to expand or relocate to a new location in the U.S.? If so, Mi ... Read More

View More

Economic Development Contacts